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Caroline Jochems Selected Research

Castration

1/2021Phase I study of a multitargeted recombinant Ad5 PSA/MUC-1/brachyury-based immunotherapy vaccine in patients with metastatic castration-resistant prostate cancer (mCRPC).
10/2016Samarium-153-EDTMP (Quadramet®) with or without vaccine in metastatic castration-resistant prostate cancer: A randomized Phase 2 trial.
4/2014A combination trial of vaccine plus ipilimumab in metastatic castration-resistant prostate cancer patients: immune correlates.
7/2013Up-regulation of proliferative and migratory genes in regulatory T cells from patients with metastatic castration-resistant prostate cancer.

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Caroline Jochems Research Topics

Disease

39Neoplasms (Cancer)
01/2022 - 05/2011
13Carcinoma (Carcinomatosis)
01/2020 - 05/2011
7Arthritis (Polyarthritis)
01/2015 - 01/2005
6Prostatic Neoplasms (Prostate Cancer)
01/2021 - 12/2012
6Osteoporosis
01/2015 - 01/2005
5Rheumatoid Arthritis
06/2011 - 01/2005
4Neoplasm Metastasis (Metastasis)
01/2021 - 05/2014
4Breast Neoplasms (Breast Cancer)
01/2020 - 10/2013
3Colorectal Neoplasms (Colorectal Cancer)
11/2022 - 11/2015
2Human Influenza (Influenza)
01/2021 - 02/2014
2Papillomavirus Infections
01/2021 - 01/2020
2Injection Site Reaction
11/2015 - 03/2014
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
10/2013 - 01/2013
2Experimental Arthritis
06/2011 - 02/2010
2Inflammation (Inflammations)
12/2010 - 01/2005
2Bone Resorption
02/2010 - 01/2005
1Persistent Infection
06/2021
1Recurrent respiratory papillomatosis
06/2021
1Sarcoma (Soft Tissue Sarcoma)
01/2021
1Infections
01/2021
1Chordoma
01/2021
1Necrosis
01/2019
1Confusion (Bewilderment)
11/2016
1Sudden Death
11/2016
1Edema (Dropsy)
11/2015

Drug/Important Bio-Agent (IBA)

20VaccinesIBA
11/2022 - 11/2011
7AntigensIBA
06/2021 - 01/2005
7Proteins (Proteins, Gene)FDA Link
06/2021 - 05/2014
7Immunoglobulin G (IgG)IBA
12/2020 - 10/2015
6avelumabIBA
11/2022 - 10/2015
6Estrogens (Estrogen)FDA Link
06/2011 - 01/2005
5Brachyury protein (Brachyury)IBA
01/2021 - 05/2014
4LigandsIBA
12/2020 - 10/2012
4Monoclonal AntibodiesIBA
01/2018 - 10/2015
4Docetaxel (Taxotere)FDA Link
10/2016 - 10/2013
4Estradiol (Delestrogen)FDA LinkGeneric
06/2011 - 10/2007
3Transcription Factors (Transcription Factor)IBA
01/2021 - 05/2014
3Papillomavirus Vaccines (HPV Vaccines)IBA
01/2021 - 01/2020
3Interleukin-12 (IL 12)IBA
01/2020 - 10/2015
3CytokinesIBA
01/2020 - 10/2012
3PerforinIBA
01/2017 - 12/2014
3PROSTVACIBA
10/2016 - 02/2014
3Cancer VaccinesIBA
11/2015 - 05/2011
3Prostate-Specific Antigen (Semenogelase)IBA
08/2014 - 02/2014
3Raloxifene Hydrochloride (Evista)FDA Link
06/2011 - 10/2007
2Bevacizumab (Avastin)FDA Link
11/2022 - 07/2016
2AntibodiesIBA
01/2021 - 12/2016
2Transforming Growth Factors (Transforming Growth Factor)IBA
12/2020 - 04/2018
2Neoplasm Antigens (Tumor Antigens)IBA
01/2020 - 06/2016
2Histone Deacetylase InhibitorsIBA
01/2020 - 01/2018
2entinostat (MS 275)IBA
01/2020 - 01/2018
2Granzymes (Granzyme)IBA
01/2017 - 12/2016
2Peptides (Polypeptides)IBA
12/2014 - 02/2014
2TamoxifenFDA LinkGeneric
05/2014 - 10/2013
2IpilimumabIBA
04/2014 - 12/2012
2Selective Estrogen Receptor Modulators (SERM)IBA
06/2011 - 10/2007
2CollagenIBA
12/2010 - 10/2007
2Collagen Type II (Type II Collagen)IBA
02/2010 - 01/2005
2salicylhydroxamic acid (SHAM)IBA
02/2010 - 01/2005
2LY 117018IBA
12/2009 - 10/2007
1Adenovirus VaccinesIBA
06/2021
1smallpox and monkeypox vaccine modified vaccinia ankara-bavarian nordicIBA
01/2021
1Immunoconjugates (Immunoconjugate)IBA
01/2020
1Immune Checkpoint InhibitorsIBA
01/2020
1Ado-Trastuzumab EmtansineIBA
01/2020
1DNA (Deoxyribonucleic Acid)IBA
01/2019
1Histones (Histone)IBA
01/2019
1InterleukinsIBA
04/2018
1Interleukin-15 Receptors (Interleukin 15 Receptor)IBA
04/2018
1Death Domain ReceptorsIBA
01/2018
1VorinostatFDA Link
01/2018
1Histone Deacetylases (Histone Deacetylase)IBA
01/2018
1ALT-803IBA
09/2017
1Interleukin-15 (Interleukin 15)IBA
09/2017
1Fc Receptors (Fc Receptor)IBA
01/2017
1Complement System Proteins (Complement)IBA
01/2017
1concanamycin AIBA
01/2017
1Trastuzumab (Herceptin)FDA Link
12/2016
1Interleukin-2 (IL2)IBA
12/2016
1pertuzumabIBA
12/2016
1Cetuximab (Erbitux)FDA Link
12/2016
1Alanine Transaminase (SGPT)IBA
11/2016
1Aspartate Aminotransferases (Aspartate Transaminase)IBA
11/2016
1Interferon-alpha (Interferon Alfa)IBA
11/2016
1Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA
11/2016
1RadiopharmaceuticalsIBA
10/2016
1samarium Sm-153 lexidronam (Quadramet)FDA Link
10/2016
1DiaminesIBA
10/2016
1Organophosphonates (Phosphonates)IBA
10/2016
1epacadostatIBA
06/2016
1GlucocorticoidsIBA
01/2015
1Bacterial VaccinesIBA
12/2014
1HLA-A2 Antigen (HLA A2 Antigen)IBA
12/2014

Therapy/Procedure

17Therapeutics
01/2022 - 10/2007
7Immunotherapy
11/2022 - 12/2012
4Castration
01/2021 - 07/2013
4Drug Therapy (Chemotherapy)
01/2021 - 11/2011
2Hormone Replacement Therapy (Therapy, Hormone Replacement)
03/2011 - 10/2007
2Ovariectomy (Oophorectomy)
02/2010 - 01/2005
1Intravenous Administration
01/2021